It can cause serious side effects such as muscle damage and
Details about a common statin medic… Simvastatin is a prescription drug that lowers cholesterol and triglycerides and reduces the risk of heart disease
It may be given to you for other reasons
But in 28 major clinical trials of statins, only 2 percent of participants have been 75 years or older
The risk of CHD mortality was
Uses Warnings Before taking Dosage Side effects Interactions FAQ What is simvastatin? Simvastatin belongs to a group of drugs called
Statins are also particularly useful in patients with
American visitors to Florida were 63% more likely to have died from a drug overdose compared to visitors to the rest of the U
During the same time period, the percentage of overdose deaths involving injections fell from 22
The substantial reductions in
1 In 2021, 106,699 drug overdose deaths occurred in the United States
) Those who took simvastatin had an 87
Information is To date, a few cases of overdose have been reported; the maximum dose taken was 3
There is no known risk for physical dependence
9 people out of every 100,000 people exposed to simvastatin for one full year (the average incidence for hospitalized rhabdomyolysis Side Effects
with non-significant numerical differences favouring ezetimibe/simvastatin for nonfatal MI and cardiac death
poisoning by overdose of substance; poisoning by wrong substance given or taken in error; underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed; Note
Drug overdose is the leading cause of accidental death in the United States, with opioids being the most common drug
The largest percentage of males were aged 35–44 and the largest percentage of females were aged 35–44
The inhibition of HMG-CoA reductase induces
Simvastatin also decreased the risk of major coronary events (a composite endpoint comprised of non-fatal MI or CHD death) by 27 % (p < 0
Once hydrolyzed, simvastatin competes with HMG-CoA for HMG-CoA reductase
It is a semi-synthetic derivative of lovastatin, the first FDA-approved statin
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In the cases of acute rivaroxaban overdose, conservative management without prothrombin complex concentrate or other coagulation factors may be sufficient if renal function is normal and there is no bleeding
As overdose deaths rise, so do calls to expand the network of supervised injecting rooms in the state
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