Ivermectin and its related drugs act by interfering with the nerve and muscle functions of helminths and insects
Postpublication review confirmed that while the review article appropriately describes the mechanism of action of ivermectin, the cited sources
Asiya Kamber Zaidi 1 Puya Dehgani-Mobaraki 1
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Studies that included some form of re‐treatment This review article aims to discuss the probable mechanisms of action of ivermectin against SARS-CoV-2 by summarizing the available literature over the years
, is frequently used in veterinary medicine, due to its broad spectrum of activity, high efficacy and wide margin of safety
Ivermectin: Inhibition of importin 1 heterodimer to inhibit the nuclear import of host and viral proteins This antiviral activity is due to the fact that action mechanism is based on interfering with the host regulated pathways of virus replication rather than the specific pathways of the virus
Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection (e Ivermectin has powerful antitumor effects, including the inhibition of proliferation, metastasis, and angiogenic activity, in a variety of cancer cells
Though the exact mechanism of action of ivermectin in improving rosacea is unknown, it is presumed that the anti-inflammatory and anti-parasitic activities of the medication target the etiologic factors of the disease
The mechanism of action of avermectins in Caenorhabditis elegans: correlation between activation of glutamate‐sensitive chloride current, Tryptophan 46 is a site for ethanol and ivermectin action in P2X4 receptors
21–26 In 4 of the studies, ivermectin was identified as having the Ivermectin Mechanism : Ivermectin is a member of the avermectin class of broad-spectrum antiparasitic agents which have a unique mode of action
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Management of COVID-19 in patients with seizures: Mechanisms of action of potential COVID-19 drug treatments and consideration for potential drug-drug interactions with anti-seizure medications
IMPα/β1 is a type of transporter that transports various proteins from the cytoplasm to the nucleus