Amiodarone induced thyrotoxicosis (AIT) is a form of hyperthyroidism due to treatment with antiarrhythmic drug, amiodarone
Amiodarone, upon discontinuation, can linger in the body for as much as a four-month period [13]
The risk of thyroid disorder increased with exposure to higher cumulative doses
Amiodarone-induced thyroid disease can be diagnosed based on classic signs and symptoms of either hypothyroidism or hyperthyroidism or, more commonly, by routine (every 3–6 months) thyroid Amiodarone, a class III antiarrhythmic drug, has multiple effects on myocardial depolarization and repolarization that make it an extremely effective antiarrhythmic drug
Amiodarone, a class III antiarrhythmic drug, has multiple effects on myocardial depolarization and repolarization that make it an extremely effective antiarrhythmic drug
They may contribute to the occurrence of both Amiodarone- Induced Thyrotoxicosis (AIT) and Amiodarone-Induced Hypothyroidism
The mechanism of amiodarone-induced thyroid dysfunction may involve the large iodine content of the drug
Amiodarone induced thyroid dysfunction: pathophysiology, diagnosis and management Adverse Drug React Toxicol Rev
The AIT type 1 usually occurs in patients with known or previously undiagnosed thyroid dysfunction or
The type of amiodarone-induced thyroid dysfunction may depend on the patient’s underlying thyroid condition and iodine intake