Ritonavir, a strong cytochrome P450 (CYP) 3A4 inhibitor and a P-glycoprotein (P-gp) inhibitor, is coadministered with nirmatrelvir to increase the blood concentration of nirmatrelvir, thereby making it effective against SARS-CoV-2
Metoprolol has an average rating of 5
Topiramate is contra-indicated in nephrolithiasis and glaucoma
Verapamil and lithium are the preventive drugs of first choice and the most widely used in first-line preventive treatment
Topamax is another drug used as a first-line treatment option for migraine prophylaxis
Published on November 23, 2022
Cimetidine, danazol, dextropropoxyphene, diltiazem, risperidone, quetiapine 1, ticlopidine, verapamil: Ethosuximide: Antimicrobials: Isoniazid: Lamotrigine:
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The other anticonvulsant that has been studied extensively and has reported efficacy in migraine prophylaxis is topiramate (Topamax) (see Table 1)
Verapamil may be used to treat angina, arrhythmias, or to lower blood pressure