Drugs
Approved veterinary products are available with a trimethoprim-to-sulfadiazine ratio of 1:4; dosages are based on the total mg of the combination
24 mg/kg, PO, q 12 h; 30 mg/kg, PO, q 12–24 h
5 mg/kg, IM, once to three times daily for 5–14 days
The other sixteen guinea pigs were used as untreated controls and received a placebo during the study
Aplastic anemia—unusual weakness or fatigue, dizziness, headache, trouble breathing, increased bleeding or bruising, fever, chills, cough, or sore throat
However, the dose is usually not more than 1600 mg of sulfamethoxazole and 320 mg
2 g orally one time, followed by 1 g orally every 6-12 hours for 10 to 14 days
Antibiotic Dosages for Use in Guinea Pigs
For oral administration: Calves, goats and sheep: Twice daily 5 g per 100 kg body weight for 4 - 7 days
Sixteen unin-
Trimethoprim/sulfa — Tissue necrosis Guinea pigs : 15-30 mg/kg topically q21-28d × 2 treatments (q14d if Demodex) 26: Most species/use 30 mg/kg with Sarcoptes: Sulfadimethoxine: 10-15 mg/kg PO q12h 33: All species/coccidiosis : 25-50 mg/kg PO q24h × 10 days 66: Chinchillas, guinea pigs, hamsters/coccidiosis : A single 30 mg/kg dose of trimethoprim-sulfamethoxazole (TMS) was administered orally (n = 17) and intravenously (n = 13) in a crossover study design, with 10-day washout period, to determine drug Bactrim (Sulfamethoxazole and Trimethoprim Oral/Injection) received an overall rating of 9 out of 10 stars from 1253 reviews
soreness of the muscles
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