Generic Name (S): ondansetron HCl Uses Uses This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment ( chemotherapy) and radiation Ondansetron is one of the medications most commonly used for the empiric treatment of nausea and vomiting
Zofran (ondansetron) is an antiemetic and selective 5-HT3 receptor antagonist prescribed for the treatment of nausea and vomiting due to cancer
15 mg/kg doses, up to a maximum of 16 mg per dose, infused intravenously over 15 minutes
Generic name: ondansetron (oral) [ on-DAN-se-tron ] Brand names: Zofran, Zofran ODT, Zuplenz Drug class: 5HT3 receptor antagonists Medically reviewed by
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Ondansetron oral tablets are prescribed for nausea and vomiting in certain situations
12 to 17 years of age: 8 mg administered 30 minutes before the start of chemotherapy, with a subsequent 8-mg dose 8 hours after the first dose
Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting
ZOFRAN oral solution, 4 mg/5 mL, is a clear, colorless to light yellow liquid with a characteristic strawberry According to sales distribution data, ondansetron IV 32 mg premixed bags accounted for less than 1% of ondansetron IV sales (vials, bags, etc
15 mg/kg doses, up to a maximum of 16 mg per dose, infused intravenously over 15 minutes
More typical pregnancy nausea is managed by a much Keep Zofran Tablets in a cool, dry place where it stays below 30°C, and away from bright sunlight
Oral administration of ondansetron up to 15 mg/kg per day (approximately 6 times the maximum recommended human oral dose of 24 mg per day, based on body surface area) did not affect fertility or general reproductive performance of male and female rats
Adults and pediatric patients 6 months of age and older: The recommended dosage is 0
Animal studies have not shown an increased risk of infertility, birth defects or other adverse reproductive outcomes and there are limited data available about human pregnancy outcomes following exposure to ondansetron
It is approved for use in adults and children over the age of 4
Protect from light
Was a (not terribly high-powered) study awhile back talking about an average prolongation of ~20 ms in otherwise young/healthy volunteers with routine IV dosing
Max: 16 mg/dose [PO route, highly-emetogenic chemo] Dose: 24 mg PO x1 30min before chemo; Info: use for single-day chemo regimens; do not cut/chew ODT form [PO route, moderately-emetogenic chemo] Zofran ODT package insert / prescribing information for healthcare professionals