Treatment of overdosage involves the administration of milk or antacids, which bind bisphos-phonates
8, 5
It can help to strengthen bones, making them less likely to break
Alendronate: 0
Feb 5, 2021 Home CCC OVERVIEW The ECG is important in the assessment and management of poisoned patients for: screening diagnosis prognosis monitoring
A vast majority
Its drug profile includes many recognized side effects, and the literature
This drug may cause jawbone problems
Before Using Proper Use Precautions Side Effects Products and services Proper Use Drug information provided by: Merative, Micromedex ® This medicine
Bisphosphonates Alendronate Overview Alendronate is a prescription medication used to treat osteoporosis and Paget's disease in men and women
What is alendronate? Alendronate is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure
The prescription drug Fosamax (the generic is alendronate sodium) is a medication which has been prescribed to hundreds of thousands of postmenopausal women to treat osteoporosis and help increase bone mass thereby reducing the chance of spinal or non-spinal fractures
Signs of sodium-channel blockade: QRS broadening (> 100 ms) and positive R’ wave in aVR (> 3mm) NB
Each Alendronate D3 tablet contains 70 mg, of alendronate sodium and 70 mcg or 140 mcg of colecalciferol as the active ingredients
Alendronate and naproxen are synergistic for development of gastric ulcers (Vol 161, pg 107, 1921)
Fatal esophageal perforation with alendronate
upset stomach
Tachycardia (17% of all VPA overdose patients) Hemodynamic instability, such as hypotension (~25% of those with levels >850mg/L) Valproate toxicity does not manifest as cardiac sodium channel blockade
For this use, you’ll need to take the generic form of Fosamax, called alendronate
5 months; interquartile range [IQR], 6
This syndrome is associated with an increased risk of polymorphic ventricular tachycardia (VT) and a characteristic life-threatening cardiac arrhythmia also known as torsades de
The risk may be higher with longer use, cancer, dental problems, ill-fitting dentures, anemia, blood clotting problems, or infection
Patients who just ingested an extended-release formulation of bupropion may have minimal symptoms initially
Clin Toxicol (Phila)
Potassium plays a key role in both depolarization and repolarization, which is why potassium imbalance may cause dramatic ECG changes
Descriptions
All our ECGs are free to reproduce for educational purposes, provided: The image is credited to litfl
ECG changes and arrhythmias caused by digoxin were discussed previously
This is a condition that causes your bones to get weaker and be more likely to break
Treatment for a Fosamax Overdose
1 Adverse cardiac effects include moderate negative inotropic action and depression of all major conduction pathways
Doses > 3g are associated with coma